Evidence map›Paper›PMID 42696208›Full record

ReviewInflammopharmacology2026

Molecular target for neuroinflammation and pain management: transient receptor potential vanilloid 1.

Zunera Chauhdary, Muhammad Saad Masood, Muhammad Irfan, Amina Shafi, Duryab Rafique, Abeesha Arif, Maryam Akmal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zunera ChauhdaryFaculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan. zunerach57@gmail.com.
Muhammad Saad MasoodDepartment of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
Muhammad IrfanFaculty of Pharmaceutical Sciences, Department of Pharmaceutics, Government College University, Faisalabad, Pakistan.
Amina ShafiFaculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Duryab RafiqueFaculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Abeesha ArifFaculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Maryam AkmalFaculty of Pharmaceutical Sciences, Department of Pharmaceutics, Government College University, Faisalabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel and polymodal sensor of noxious heat, protons, capsaicin and endogenous lipids. The wide variety of functions of TRPV1 in pain transmission, inflammatory pathways and neurological disorders has triggered efforts to understand the molecular mechanisms underlying these functions, particularly pain and neuroinflammation. The molecular structure and its tetrameric structure, temperature and ligand dependent activation and post-translational modification are discussed. It also covers the Ca

Indexed as

Calcium signaling (Ca2⁺ influx)Capsaicin-sensitive receptorsImmune–neural interactionsNeurodegenerative diseasesNeuroinflammationPain modulationTransient receptor potential vanilloid 1 (TRPV1)TRPV1-targeted therapeutics

Identifiers

PMID42696208

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.