ArticleeLife2026
Realistic coupling enables flexible macroscopic traveling waves in the mouse cortex.
Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
Abstract
Traveling waves are ubiquitous in neuronal systems across different spatial scales. While microscopic and mesoscopic waves are relatively well studied, the emergence of macroscopic traveling waves remains less understood. Here, by modeling the mouse cortex using spatial transcriptomic and connectivity data, we show that realistic cortical connectivity can generate a significantly higher level of macroscopic traveling waves than artificial local and uniform connectivity across multiple oscillation frequency bands, with the strongest advantage appearing in the theta, alpha, and beta frequency bands. By probing the model in different dynamic regimes, we find that macroscopic wave activity depends on both network connectivity and excitatory coupling strength, with a non-monotonic dependence on coupling. Together, our work shows how flexible macroscopic traveling waves can emerge in the mouse cortex and offers a computational framework to further study traveling waves in the mouse brain at the single-cell level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.