Evidence map›Paper›PMID 42699295›Full record

ArticleFood chemistry: X2026

Ultrasound-assisted natural deep eutectic solvent for the extraction of flavonoids from hawk tea: COSMO-RS screening, optimization, and

Jie Li, Pei Li, Lu Zhuang, Juecheng Lei, Yuyi Hu, Xiuming Zhai, Fuliang Xiao, Juan Yang, Guang Yang, Dan Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jie LiResearch Institute of Tea, Chongqing Academy of Agricultural Sciences, Chongqing, China.
Pei LiCollege of Life Sciences and Agri-forestry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China.
Lu ZhuangCollege of Life Sciences and Agri-forestry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China.
Juecheng LeiCollege of Life Sciences and Agri-forestry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China.
Yuyi HuCollege of Life Sciences and Agri-forestry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China.
Xiuming ZhaiResearch Institute of Tea, Chongqing Academy of Agricultural Sciences, Chongqing, China.
Fuliang XiaoResearch Institute of Tea, Chongqing Academy of Agricultural Sciences, Chongqing, China.
Juan YangResearch Institute of Tea, Chongqing Academy of Agricultural Sciences, Chongqing, China.
Guang YangResearch Institute of Tea, Chongqing Academy of Agricultural Sciences, Chongqing, China.
Dan WangCollege of Life Sciences and Agri-forestry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China.
Qiyang ChenCollege of Life Sciences and Agri-forestry, Southwest University of Science and Technology, Mianyang, Sichuan 621010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An ultrasound-assisted natural deep eutectic solvent (UAE-NADES) method was developed to extract hawk tea flavonoids (HTFA). Conductor-like screening model for realistic solvents (COSMO-RS)-guided screening and experimental validation identified betaine-urea as the optimal solvent. Using response surface methodology, we optimized the UAE-NADES system for HTFA, achieving a yield of 832.96 ± 14.72 mg RE/g DW. Mechanistic studies revealed that the UAE-NADES system facilitated extraction

Indexed as

COSMO-RSFlavonoidsHawk teaIn vitro starch digestionNatural deep eutectic solvent (NADES)Ultrasound-assisted extraction (UAE)

Identifiers

PMID42699295
PMCPMC13543104

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.