Evidence map›Paper›PMID 42700334›Full record

ArticleMolecular biology reports2026

Chemical profiling of Egregia menziesii and anti-inflammatory potential in LPS-activated RAW 264.7 macrophages.

Omar Arroyo-Xochihua, Alberto Sánchez-Medina, Óscar López-Franco, Tatiana N Olivares-Bañuelos, Rossana C Zepeda

Abstract read
In one paragraph

Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Omar Arroyo-XochihuaDoctorado en Ciencias Biomédicas, Centro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa, Veracruz, México.ORCID http://orcid.org/0000-0002-6910-0689
Alberto Sánchez-MedinaLaboratorio de Farmacología y Quimiometría, Instituto de Química Aplicada, Universidad Veracruzana, Xalapa, México.ORCID http://orcid.org/0000-0002-3017-9801
Óscar López-FrancoLaboratorio de Medicina Traslacional, Universidad Veracruzana, Xalapa, Veracruz, México.
Tatiana N Olivares-BañuelosInstituto de Investigaciones Oceanológicas, Universidad Autónoma de Baja California, Ensenada, Baja California, México.ORCID http://orcid.org/0000-0002-2989-1359
Rossana C ZepedaLaboratorio de Biomedicina Integral y Salud, Centro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa, Veracruz, México. rzepeda@uv.mx.ORCID http://orcid.org/0000-0003-4442-1141

Funding

PhD scholarship by SECIHTI, Mexico 1221205
6 · The paper itself

Abstract

backgroundEgregia menziesii (E. menziesii) is recognized for its anticancer and hypoglycemic properties. Chemically, it contains compounds with potential anti-inflammatory activity. Within the immune system, macrophages play an essential role in containing and eradicating pathogens through phenotypic polarization. METHODS AND

resultsThe ethanol and water (1:1 v/v) (EtOH: H

conclusionsE. menziesii safely regulates macrophage behavior, IL-1β and IL-6 release and promotes scratch area reduction. The immunomodulatory effect could be linked to the presence of sulfate polysaccharides and mannitol.

Indexed as

Anti-Inflammatory AgentsMacrophagesPhaeophyceaePlant ExtractsAnimalsCell SurvivalCytokinesLipopolysaccharidesMicePhagocytosisPolysaccharidesRAW 264.7 CellsAnti-Inflammatory AgentsCytokinesLipopolysaccharidesPlant ExtractsPolysaccharidesChemometricsCytokinesImmune systemInflammationSeaweeds

Identifiers

PMID42700334
PMCPMC13546325

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.