Evidence map›Paper›PMID 42701456›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2026

Chondroitin sulfate modulates gut microbiota to improve bone metabolism and reduce locomotion problems in yellow-feathered broilers.

Yuyang Xue, Min Yao, Xiangjian Peng, Fang Wang, Shanshan Nan, Wei Jing, Fei Zhang, Xueqiang Liu, Zhonglin Liu, Cunxi Nie and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuyang XueCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.
Min YaoSchool of Medicine, Shihezi University, Shihezi 832003, Xinjiang, China.
Xiangjian PengCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.
Fang WangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.
Shanshan NanCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.
Wei JingCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.
Fei ZhangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.
Xueqiang LiuXinjiang Chuangyu Poultry Breeding Co., Ltd., Shihezi 832021, Xinjiang, China.
Zhonglin LiuXinjiang Chuangyu Poultry Breeding Co., Ltd., Shihezi 832021, Xinjiang, China.
Cunxi NieCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.
Wenju ZhangCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, Xinjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chondroitin sulfate (CS) is known to promote bone health, but its effects on skeletal development and gut microbiota in yellow-feathered broilers remain largely unexplored. This study aimed to evaluate the effects of CS on bone health, growth performance, and intestinal flora in broilers. A total of 720 one-d-old Jinling yellow-feathered broilers (initial body weight 37.0 ± 0.5 g) were randomly divided into four treatment groups, each with nine replicates of 20 birds. The control group was fed a basal diet (CON), while the experimental group was supplemented with low (LCS), medium (MCS), or high CS (HCS) levels (0.05%, 0.15%, or 0.30%) for 30 d. Samples were collected every 10 d during a supplementation period of 30 d and again at 63 d to investigate the effect of early supplementation of CS on bone development later in life. Chondroitin sulfate supplementation improved broiler growth performance only at the beginning of the study. Compared with the CON group, the MCS group significantly increased tibial weight and length, and improved mid-segment geometric parameters, including vertical wall thickness (WTv), cross-sectional moment of inertia (CSMI), and cross-sectional area (CSA) (

Indexed as

Bone developmentBone healthBroilerChondroitin sulphateGut microbiology

Identifiers

PMID42701456
PMCPMC13545383

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.