ArticleCell and tissue banking2026
Electroconductive and biodegradable scaffold based on alginate/polyaniline hydrogel loaded with green synthesized magnesium oxide nanoparticles for bone regeneration.
Article in Cell and tissue banking, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone fractures are increasing globally, and the limitations of traditional grafts have encouraged the development of advanced biomaterial-based strategies for bone repair. In this study, we developed an injectable alginate/polyaniline (Alg/PANI) hydrogel containing green-synthesized magnesium oxide nanoparticles (MgONPs). The Alg/PANI/NPs scaffold exhibited favorable cytocompatibility and bioactivity, enhancing osteoblast-like cell viability/proliferation to 115.7% by day 3 and reducing hemolysis to 4.67%, indicating improved hemocompatibility. In addition, the scaffold was associated with macrophage polarization toward the pro-healing M2 phenotype, supported by morphological changes and increased TGF-β1 expression. It also established a regenerative microenvironment associated with enhanced antioxidant status, including a 2.5-fold increase in superoxide dismutase (SOD) activity, a 65% reduction in malondialdehyde (MDA), and a 2.1-fold increase in nitric oxide (NO) levels. Overall, these findings indicate that the Alg/PANI/NPs hydrogel is a promising multifunctional biomaterial that supports regenerative responses through immunomodulatory, antioxidative, and cytocompatible effects.
Indexed as
Identifiers
42702663What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.