Evidence map›Paper›PMID 42708183›Full record

ArticleThe European journal of neuroscience2026

Hyperdopaminergic States Bias Explorations-Exploitation Trade-Off in Foraging and Impair Survival.

Wanhao Chi, Wenqin Fu, Cristianne R M Frazier, Liwen Xu, Jeff A Beeler, Xiaoxi Zhuang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The European journal of neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wanhao ChiDepartment of Neurobiology, The University of Chicago, Chicago, Illinois, USA.
Wenqin FuDepartment of Neurobiology, The University of Chicago, Chicago, Illinois, USA.
Cristianne R M FrazierCommittee on Neurobiology, The University of Chicago, Chicago, Illinois, USA.
Liwen XuDepartment of Neurobiology, The University of Chicago, Chicago, Illinois, USA.
Jeff A BeelerDepartment of Neurobiology, The University of Chicago, Chicago, Illinois, USA.
Xiaoxi ZhuangDepartment of Neurobiology, The University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-6825-3221

Funding

Genomic analysis of feeding behavior and fitness in DrosophilaR01GM100768 · NIGMS · UNIVERSITY OF CHICAGO · PI LONG, MANYUAN, ZHUANG, XIAOXI · 2012 to 2015
$1.6M
NIGMS NIH HHS R01 GM100768NIH HHS R01GM100768
6 · The paper itself

Abstract

Dopamine plays central roles in reinforcement learning and motivation, allowing animals to evaluate energetic costs and gains for efficient foraging. However, how genetic variation in dopaminergic function influences survival remains poorly understood. Here, we used Drosophila melanogaster, an established model for studying fitness, to investigate the effects of hyperdopaminergic state on survival in energetically limited environments. We used the well-characterized dopamine transporter mutant fumin (DAT

Indexed as

DopamineFeeding BehaviorAmphetamineAnimalsDopamine Plasma Membrane Transport ProteinsDrosophila melanogasterDrosophila ProteinsFemaleLearningMaleMutationAmphetamineDopamineDopamine Plasma Membrane Transport ProteinsDrosophila Proteinsdopaminefeedingfitnesslearningmotivation

Identifiers

PMID42708183
PMCPMC13551401

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.