Trial reportPhysiological research2026
Electrical Impedance Tomography-Guided Synergistic Intervention of Respiratory Muscle Training and Postural Adjustment for Lung Recruitment in Critically Ill Patients With Respiratory Failure.
Trial report in Physiological research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lung collapse and ventilation heterogeneity are common in mechanically ventilated critically ill patients. Electrical impedance tomography (EIT) enables real-time bedside monitoring of regional ventilation and may facilitate individualized respiratory management. This study evaluated the effect of EIT-guided respiratory muscle training (RMT) combined with postural adjustment on lung recruitment in patients with respiratory failure. In this single-center, prospective, randomized controlled trial, 150 patients were randomly assigned to three groups: the EIT collaborative group (EIT-guided RMT+postural adjustment), the EIT posture group (EIT-guided positioning only), and the conventional collaborative group (RMT+postural adjustment without EIT). The primary endpoint was the change in end-expiratory lung impedance (EELI). Secondary outcomes included oxygenation, respiratory mechanics, ventilation homogeneity, and clinical outcomes. Data were analyzed using ANOVA and linear mixed-effects models. The interventions were applied for up to 5 consecutive days after randomization or until ICU discharge, whichever occurred first. After 5 days, EELI increased by 18.4±7.6 % in the EIT collaborative group, which was significantly greater than the increases observed in the EIT posture group (9.1±6.2 %) and the conventional collaborative group (3.7±5.8 %) (P<0.001). CL % decreased markedly without a significant increase in OD %, while CoV and GI index indicated improved ventilation uniformity. The EIT collaborative group also showed favorable trends toward improved oxygenation and respiratory mechanics, along with shorter ventilation duration and higher extubation success rates. A significant interaction between EIT supervision intensity and intervention level was confirmed (F=6.45, P=0.011). No serious adverse events occurred. These findings suggest that EIT-guided RMT combined with postural adjustment may enhance lung recruitment and ventilation homogeneity, with potential benefits for respiratory mechanics and selected short-term clinical outcomes. Real-time EIT feedback may provide a safe, individualized strategy for respiratory rehabilitation in critically ill patients.
Indexed as
Identifiers
42708872PMC13580672What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.