Evidence map›Paper›PMID 42709403›Full record

ArticleGigaScience2026

A chromosome-level, haplotype-resolved genome assembly for the barn owl, Tyto alba.

Hugo Corval, Anne-Lyse Ducrest, Marianne Bachmann Salvy, Allison Burns, Alexandros Topaloudis, Céline Simon, Elisa Cora, Daniel Cavaleri, Bettina Almasi, Alexandre Roulin and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GigaScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hugo CorvalDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0009-0008-1842-7754
Anne-Lyse DucrestDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0000-0001-6412-2769
Marianne Bachmann SalvyDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0009-0006-1528-8168
Allison BurnsBioinformatics Competence Center (BICC), École Polytechnique Fédérale de Lausanne, Bâtiment AAB, Station 19, CH-1015 Lausanne, Switzerland.ORCID 0000-0001-7153-3160
Alexandros TopaloudisDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-0909-8695
Céline SimonDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0009-0006-5680-2274
Elisa CoraGene Expression Core Facility (GECF), School of Life Sciences, École Polytechnique Fédérale de Lausanne, Bâtiment SV, Station 19, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-5065-362X
Daniel CavaleriGene Expression Core Facility (GECF), School of Life Sciences, École Polytechnique Fédérale de Lausanne, Bâtiment SV, Station 19, CH-1015 Lausanne, Switzerland.ORCID 0009-0009-2113-0510
Bettina AlmasiSwiss Ornithological Institute, Seerose 1, CH-6204 Sempach, Switzerland.ORCID 0000-0003-4962-8117
Alexandre RoulinDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0000-0003-1940-6927
Christian IseliBioinformatics Competence Center (BICC), École Polytechnique Fédérale de Lausanne, Bâtiment AAB, Station 19, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-2296-2863
Nicolas GuexBioinformatics Competence Center (BICC), École Polytechnique Fédérale de Lausanne, Bâtiment AAB, Station 19, CH-1015 Lausanne, Switzerland.ORCID 0000-0001-6023-0519
Tristan CumerDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-0276-7462
Jérôme GoudetDepartment of Ecology and Evolution, University of Lausanne, Biophore, Quartier UNIL-Sorge, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-5318-7601

Funding

Swiss National Science Foundation 310030_215709
6 · The paper itself

Abstract

backgroundRecent advances in long-read sequencing have enabled near telomere-to-telomere (T2T) assemblies across diverse taxa. However, avian genomes remain challenging due to numerous microchromosomes, small, typically <20Mb, DNA molecules that are gene-, GC-, and repeat-rich. As a consequence, microchromosomes are often missing from genome assemblies.

resultsHere, we present a chromosome-level, haplotype-resolved genome assembly for the Western barn owl (Tyto alba). Using a trio-binning strategy with Illumina parental reads combined with PacBio HiFi and Oxford Nanopore Technologies data, we generated 2 phased contig sets. These were scaffolded into 40 linkage groups using a linkage map. Comparative analyses identified unplaced HiFi scaffolds corresponding to microchromosomes, which we integrated into 6 additional microchromosomes using long reads information. The 2 assemblies present 46 chromosomes, matching the karyotype of the species. They exhibit strong synteny between parental haplotypes, except for a ∼38 Mb complex region on chromosome 7 containing nested inversions.

conclusionsThis high-quality reference provides a haplotype-resolved and chromosome-level genome for Strigiformes, enabling fine-scale studies of structural variation and avian genome evolution.

Indexed as

ChromosomesGenomeGenomicsHaplotypesStrigiformesAnimalsChromosome MappingGenetic LinkageSequence Analysis, DNAchromosomal inversionchromosome-levelgenome assemblyhaplotype-resolvedmicrochromosomesStrigiformesTyto alba

Identifiers

PMID42709403
PMCPMC13615541

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.