Evidence map›Paper›PMID 42711737›Full record

ArticleGeneral thoracic and cardiovascular surgery cases2026

Early biological reactions to a novel hybrid knit fabric inducing autologous tissue ingrowth implanted in a small infant.

Takashi Kido, Shintaro Nemoto, Jun Narita, Hidekazu Ishida, Ryo Ishii, Takayoshi Ueno, Shigeru Miyagawa

Abstract read
In one paragraph

Article in General thoracic and cardiovascular surgery cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Takashi KidoDepartment of Cardiovascular Surgery, The University of Osaka Graduate School of Medicine, Osaka, Japan. kido.surg1@osaka-u.ac.jp.ORCID http://orcid.org/0000-0002-8881-373X
Shintaro NemotoDepartment of Thoracic and Cardiovascular Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Jun NaritaDepartment of Pediatrics, The University of Osaka Graduate School of Medicine, Osaka, Japan.
Hidekazu IshidaDepartment of Pediatrics, The University of Osaka Graduate School of Medicine, Osaka, Japan.
Ryo IshiiDepartment of Pediatrics, The University of Osaka Graduate School of Medicine, Osaka, Japan.
Takayoshi UenoDepartment of Cardiovascular Surgery, The University of Osaka Graduate School of Medicine, Osaka, Japan.
Shigeru MiyagawaDepartment of Cardiovascular Surgery, The University of Osaka Graduate School of Medicine, Osaka, Japan.

Funding

KAKENHI 26K19215Teijin Pharma Teijin Pharma
6 · The paper itself

Abstract

back groundPatch augmentation of the right ventricular outflow tract (RVOT) is frequently required in pediatric patients with stenosis or atresia affecting the right ventricle-to-pulmonary artery continuity. However there have been no ideal patch materials for pediatric patients. CASE PRESENTATION: A 1-month-old infant with pulmonary atresia with an intact ventricular septum underwent surgical pulmonary valvotomy and RVOT reconstruction using a novel hybrid wrap-knitted patch designed for autologous tissue ingrowth. Ten months postoperatively, for recurrent severe pulmonary valve stenosis, the patient underwent repeat RVOT reconstruction. Histological examination of the excised hybrid patch revealed that both surfaces were covered with regenerated tissue composed of smooth muscle cells, blood vessels, and collagen fibers. Transmission electron microscopy confirmed that the regenerated tissue contained feature mature fibroblasts and capillaries, demonstrating sufficient development of regenerated tissue.

conclusionsHistological findings of the hybrid wrap-knit fabric patch excised in redo surgery 10 months after the initial surgery showed potential macrophage-fibroblast interaction, promoting tissue remodeling in the new fabric.

Indexed as

Biodegradable polymerCongenital heart surgerySurgical materialTissue regeneration

Identifiers

PMID42711737
PMCPMC13555954

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.