Evidence map›Paper›PMID 42712328›Full record

ArticleFrontiers in ophthalmology2026

Corneal neurotization for neurotrophic keratopathy: a case report of two patients from different age groups.

Hamad M Alsulaiman, Huda AlGhadeer

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In one paragraph

Article in Frontiers in ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hamad M AlsulaimanOculoplastics and Orbit Division, King Khaled Eye Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Huda AlGhadeerAnterior Segment Division, King Khaled Eye Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To describe the techniques and the successful outcomes of corneal neurotization (CN) for the treatment of neurotrophic keratopathy (NK) in two patients from different age groups. Methods: A detailed clinical examination and comprehensive systemic workup were performed to determine the etiology of NK. Both cases were managed surgically with CN and followed for 3 years postoperatively at the King Khaled Eye Specialist Hospital & Research Center, Riyadh, Saudi Arabia. Results: Two eyes of a 66-year-old male and a 22-month-old boy who were diagnosed with NK and refractory to conservative therapy underwent CN. The first patient underwent indirect corneal neurotization for the management of NK in the right eye from the ipsilateral infraorbital nerve using a sural nerve interposition graft from the left leg, while the second patient underwent indirect corneal neurotization for the management of NK in the left eye from the contralateral right supraorbital nerve using a sural nerve interposition graft from the left leg. The symptoms improved following the procedure as well as the corneal sensation, with improvement of the NK in both patients. At the three-year follow-up, our patients showed no complications or NK recurrence. Conclusions: CN is a valuable surgical technique for the management of recalcitrant NK and possibly for restoring corneal sensation in some with NK prior to the development of irreversible stromal damage.

Indexed as

corneal neurotizationcorneal sensationkeratitiskeratopathyneurotrophic

Identifiers

PMID42712328
PMCPMC13549859

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.