Evidence map›Paper›PMID 42712474›Full record

Articlenpj women's health2026

Citizen science reveals comorbidities in endometriosis with no shift in vaginal microbiome composition.

Inas Rahou, Thies Gehrmann, Sarah Ahannach, Camille Nina Allonsius, Ilke De Boeck, Tim Van Rillaer, Francesca Donders, Veronique Verhoeven, Gilbert Donders, Stijn Wittouck and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in npj women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Inas RahouLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.
Thies GehrmannLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.
Sarah AhannachLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.
Camille Nina AllonsiusLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.
Ilke De BoeckLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.
Tim Van RillaerLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.
Francesca DondersDepartment of Gynaecology, Brugmann University Hospital, A. Van Gehuchtenplein 4, Brussel, Belgium.
Veronique VerhoevenU-MaMi Centre of Excellence, University of Antwerp, Antwerp, Belgium.
Gilbert DondersFemicare VZW, Clinical Research for Women, Gasthuismolenstraat 33, Tienen, Belgium.
Stijn WittouckLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.
Sarah LebeerLaboratory of Microbiology & Biotechnology, Department of Bioscience Engineering, Antwerp University, Groenenborgerlaan, Antwerp, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a chronic inflammatory condition affecting 2-10% of reproductive-aged women, most commonly presenting with pelvic pain and subfertility. While its impact on reproductive health is increasingly recognized, the vaginal microbiome's role in the pathogenesis of endometriosis is still unclear and a comprehensive map of potential co-occurring conditions remains underexplored. Leveraging data from the Isala citizen-science platform in Flanders (Belgium), we analysed vaginal microbiome profiles obtained through 16S rRNA sequencing and health data from 95 women with self-reported endometriosis and 2,279 without. While no differences were observed in vaginal microbiome composition or diversity, we identified significant associations between endometriosis and polyendocrine metabolic ovarian syndrome (previously named polycystic ovarian syndrome; OR = 2.92, 95% CI 1.71-4.78,

Indexed as

DiseasesMedical researchMicrobiology

Identifiers

PMID42712474
PMCPMC13549949

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.