Evidence map›Paper›PMID 42713445›Full record

ArticleFrontiers in veterinary science2026

Effects of rumen-protected guanidinoacetic acid on fat deposition, antioxidant capacity, fatty acid profiles in subcutaneous adipose of Tibetan sheep: integrated RNA-seq and LC-MS/MS analysis.

Zhenglu Yang, Chengdi Shi, Zhendong Liu, Rengeerli Sa, Yu Zhang, Qiurong Ji, Lijuan Han, Xiaohong Wang, Shengzhen Hou, Linsheng Gui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhenglu YangCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Chengdi ShiCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Zhendong LiuCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Rengeerli SaCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Yu ZhangCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Qiurong JiMaduo County Agriculture and Animal Husbandry Technology and Rural Revitalization Comprehensive Service Center, Qinghai, China.
Lijuan HanCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Xiaohong WangGuinan County Animal Husbandry and Veterinary Station, Qinghai, China.
Shengzhen HouCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.
Linsheng GuiCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The subcutaneous fat exerts energy storage and protective effects. However, excessive fat deposition results in waste of biological resources and compromises meat quality. According to the biological function, we hypothesized that GAA's could reduce subcutaneous fat deposition in Tibetan sheep. Methods: A total of 120 healthy weaned male lambs (2 months old) with similar body weight (17.33 ± 0.21 kg) were randomly divided into four groups, each receiving a basal diet or diet containing 0.08%, 0.10%, or 0.12% GAA. The experimental period lasted 90 days. Results: Our results showed that 0.10% GAA significantly reduced subcutaneous fat thickness ( Conclusion: In summary, 0.10% GAA reduced subcutaneous fat thickness, improved the fatty acid profile, and maintained redox homeostasis in Tibetan sheep.

Indexed as

GAALC-MS/MSRNA-Seqsubcutaneous adipose tissueTibetan sheep

Identifiers

PMID42713445
PMCPMC13552267

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.