ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2026
Postoperative Complications in Patients With Sickle Cell Disease After Total Shoulder Arthroplasty.
Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundSickle cell disease (SCD) encompasses a spectrum of genetic hematologic disorders characterized by erythrocyte sickling. Patients may experience musculoskeletal manifestations, such as osteonecrosis, which may warrant consideration for total shoulder arthroplasty (TSA). While prior literature suggests patients with SCD more frequently suffer complications after orthopaedic procedures, this is not well characterized for TSA.
methodsAdult TSA patients (older than 18 years) were identified in the 2010 to 2023 PearlDiver M170 database. Patients with SCD were matched 1:4 to patients without SCD based on age, sex, and Elixhauser Comorbidity Index (ECI). Ninety-day postoperative complications, emergency department (ED) visits, and readmissions were identified. Complications were compared for the matched cohorts by univariable analysis and multivariable analysis, controlling for age, sex, and ECI. A Kaplan-Meier survival curve was generated to compare 5-year revision rates by log-rank test.
resultsAmong TSA patients, 278 with SCD were identified and compared with 1076 matched control subjects. SCD was associated with greater odds of any aggregate adverse events (OR = 9.41), serious adverse events (OR = 5.96), and minor adverse events (OR = 10.30) (P < 0.001 for all); nearly all individual complications studied; and ED visits (OR = 5.67, P < 0.001). However, 90-day readmissions and 5-year survival to revision surgery did not differ markedly.
conclusionAfter TSA, patients with SCD had markedly elevated odds of many complications. Surgeons should consider this elevated risk with preoperative counseling and patient management. Reassuringly, elevated odds of 90-day postoperative complication did not correlate with increased rates of 5-year revision, although this finding could partially represent hesitancy to reoperate on high-risk patients.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.