Evidence map›Paper›PMID 42717076›Full record

ReviewJournal of molecular histology2026

Subcellular sirtuin signaling networks: pivotal regulators of cardiovascular homeostasis and remodeling.

Min Gao, Lanlan Li, Lin Li, Hanyu Wu, Yunkun Wu, Lei Fu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular histology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min Gao *Fujian Key Laboratory of Developmental and Neural Biology, Fujian Normal University, Fuzhou, 350117, China.
Lanlan Li *Fujian Key Laboratory of Developmental and Neural Biology, Fujian Normal University, Fuzhou, 350117, China.
Lin LiFujian Key Laboratory of Developmental and Neural Biology, Fujian Normal University, Fuzhou, 350117, China.
Hanyu WuFujian Key Laboratory of Developmental and Neural Biology, Fujian Normal University, Fuzhou, 350117, China.
Yunkun WuSchool of Future Technology, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. wuyk@fafu.edu.cn.
Lei FuFujian Key Laboratory of Developmental and Neural Biology, Fujian Normal University, Fuzhou, 350117, China. fulei@fjnu.edu.cn.

Funding

the Natural Science Foundation of China 22001250the Natural Science Foundation of Fujian Province 2023J01084
6 · The paper itself

Abstract

Sirtuins represent a family of highly conserved enzymes, initially identified as Silent Information Regulator 2 (Sir2) in yeast, where they serve as fundamental determinants of longevity. Overexpression of Sir2 in yeast significantly extends lifespan, while its deletion leads to shortened longevity. In mammals, sirtuins (SIRT1-7) represent a conserved family of NAD

Indexed as

Cardiovascular SystemHomeostasisSignal TransductionSirtuinsAnimalsCardiovascular DiseasesHumansSirtuinsAtherosclerosisCardiovascular diseaseHeart failureOxidative stressSirtuins

Identifiers

PMID42717076

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.