ReviewFrontiers in endocrinology2026
Sex-specific differences in pancreatic α-cell function.
Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Although sex is a critical biological variable determining physiology, disease risk and therapeutic responses, it remains underrepresented in biomedical research. While sex-dependent differences are well established in cardiovascular and metabolic diseases, their impact on glucagon biology is less understood. Glucagon is the key counter-regulatory hormone to insulin and plays a central role in glucose homeostasis by regulating hepatic glucose production. To date, only a limited number of studies have addressed sex-specific differences in glucagon plasma levels, secretion and α-cell function, indicating that females tend to exhibit a higher glucagon secretion. For the first time, this review summarizes the current literature on glucagon biology suggesting a sex-biased regulation of α-cell activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.