ArticleInternational journal of women's health2026
Brain Growth Trajectories in Early-Onset Fetal Growth Restriction versus Appropriate- for Gestational-Age Fetuses: A Multicenter Prospective Longitudinal Study.
Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Despite the clinical importance of brain sparing in fetal growth restriction (FGR), current data on the specific patterns of brain growth trajectory in early-onset FGR (EO-FGR) remain sparse. Methods: A multicenter prospective longitudinal study was conducted between November 2024 and February 2026. Three-dimensional tomographic ultrasound imaging was used to measure brain parameters in 36 pregnant women with EO-FGR and 36 with appropriate-for-gestational-age (AGA) fetuses at three time points: 26-28, 30-32, and 34-36 weeks of gestation. Results: The EO-FGR group initially showed delayed growth in normalized cavum septi pellucidi length (CSPL') at GA 30-32 weeks compared with the AGA group, with values of 0.03 ± 0.001 and 0.03 ± 0.01, respectively (P-value = 0.007). Further significant reductions were observed in the EO-FGR group at a GA of 34-36 weeks in the CSPL' (0.03 ± 0.01 vs 0.04 ± 0.01, P-value < 0.001), normalized CSP width (0.03 ± 0.01 vs 0.03 ± 0.01, P-value < 0.001), and normalized occipitofrontal diameter (0.32 ± 0.09 vs 0.35 ± 0.01, P-value = 0.031). Conclusion: The cavum septi pellucidi and occipitofrontal diameter may serve as early structural indicators of brain growth trajectory in EO-FGR. However, larger cohort studies are needed to validate these findings and correlate them with post-natal imaging and long-term outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.