Evidence map›Paper›PMID 42720955›Full record

ArticleJAMA network open2026

Lifelong Genetic Inhibition of PCSK9 and Hepatic Safety.

Alessia Di Costanzo, Ilaria Pirona, Laura D'Erasmo, Silvia Buonaiuto, Vincenza Colonna, Allegra Via, Daniele Tramontano, Carlo Maiorca, Marcello Arca

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAMA network open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessia Di CostanzoDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Ilaria PironaIstituto di Patologia Speciale Medica, Catholic University of the Sacred Heart, Rome, Italy.
Laura D'ErasmoDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Silvia BuonaiutoDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis.
Vincenza ColonnaDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis.
Allegra ViaDepartment of Biochemical Sciences "A. Rossi Fanelli," Sapienza University of Rome, Rome, Italy.
Daniele TramontanoDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Carlo MaiorcaDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Marcello ArcaDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42720955
PMCPMC13563260

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.