Evidence map›Paper›PMID 42722049›Full record

ArticleMitochondrion2026

Linking cellular metabolism to mitochondrial outer membrane potential.

Kaitlin Abrantes, Bethel G Beyene, Nina A Bautista, Wendy Fitzgerald, Tatiana K Rostovtseva, Sergey M Bezrukov, Megha Rajendran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mitochondrion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaitlin AbrantesEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Bethel G BeyeneEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Nina A BautistaEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Wendy FitzgeraldEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Tatiana K RostovtsevaEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Sergey M BezrukovEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Megha RajendranEunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA. Electronic address: megha.rajendran@nih.gov.

Funding

Biophysics of Large Membrane ChannelsZIAHD000072 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BEZRUKOV, SERGEY M · 2009 to 2025
$22.8M
Intramural NIH HHS ZIA HD000072
6 · The paper itself

Abstract

The voltage-dependent anion channel (VDAC) of the mitochondrial outer membrane (MOM) responds to transmembrane voltage through intrinsic gating and voltage-dependent interactions with cytosolic proteins, such as α-synuclein and β-tubulin. Despite this characteristic voltage sensitivity found in vitro, the existence of a substantial MOM potential (ΔΨ

Indexed as

HexokinasepH sensorsVDACVoltage-dependent anion channel

Identifiers

PMID42722049
PMCPMC13648930

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.