Evidence map›Paper›PMID 42723745›Full record

ArticleTranslational lung cancer research2026

Predictive modeling of peripheral blood EGFR positivity in patients with advanced primary non-small cell lung cancer.

Ying-Bo Xie, Yi-Ke Wang, Xuan Yao, Kelan Ke, Pei Ma, Feng-Nan Wang, Qin Liu, Xiao-Hong Xie, Ming Liu, Xin-Qing Lin and 2 more

Abstract read
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In one paragraph

Article in Translational lung cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ying-Bo Xie *Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.ORCID https://orcid.org/0009-0001-4253-3193
Yi-Ke Wang *Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Xuan YaoDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Kelan KeDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Pei MaDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Feng-Nan WangDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Qin LiuDepartment of Medical Imaging, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiao-Hong XieDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Ming LiuDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Xin-Qing LinDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Cheng-Zhi ZhouDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.
Zhan-Hong XieDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, National Clinical Research Centre for Respiratory Disease, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lung cancer is the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) accounting for approximately 85% of cases. Epidermal growth factor receptor ( Methods: A retrospective case-control study design was employed. Data were collected from 384 patients with NSCLC who were hospitalized at The First Affiliated Hospital of Guangzhou Medical University between June 2018 and September 2024 and met the study's inclusion criteria. The patients were categorized into two groups: the peripheral blood Results: The results of multi-factor analysis showed that gender, smoking status, pulmonary lymphangitic carcinomatosis, non-vertebral bone metastasis, brain metastasis, and liver metastasis were independent factors for the prediction of EGFR positivity in peripheral blood (P<0.05). The receiver operating characteristic (ROC) curve analysis of predicted peripheral blood Conclusions: The Gspnbl score demonstrates good predictive performance in identifying patients with a high probability of peripheral blood

Indexed as

logistic regressionNon-small cell lung cancer (NSCLC)peripheral blood EGFRpoints-scoring systemprimary treatment

Identifiers

PMID42723745
PMCPMC13557858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.