ArticlePlastic and reconstructive surgery. Global open2026
Donor-site Seroma in Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Pooled Analysis.
Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
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Abstract
Background: Seroma at the abdominal donor site is a recognized complication following deep inferior epigastric perforator (DIEP) flap breast reconstruction. Reported incidences vary widely, reflecting differences in surgical technique, patient characteristics, and outcome reporting. Consequently, this proportional meta-analysis aims to estimate the pooled incidence of abdominal donor-site seroma and evaluate potential risk factors associated with its occurrence. Methods: A systematic literature review of PubMed, Web of Science, and the Cochrane Library was performed up to June 2025. Studies reporting abdominal donor-site seroma rates following DIEP flap reconstruction were included. Data were pooled using a random-effects model (DerSimonian-Laird), and heterogeneity was assessed using Results: The search identified 1345 unique records, of which 71 studies met the inclusion criteria, comprising 12,739 patients and 16,915 DIEP flaps. A total of 736 seromas were reported, yielding a pooled incidence of 6% (95% confidence interval, 4%-7%). Heterogeneity was substantial ( Conclusions: Donor-site seroma occurs in 6% of DIEP flap reconstructions. The absence of associations with smoking or diabetes in meta-regression suggests that seroma formation may be influenced by technical and perioperative factors rather than by comorbidities.
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Registered trials
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