ArticleAnnals of medicine and surgery (2012)2026
First case description of a highly aggressive thoracopulmonary primitive neuroectodermal tumor in a Moroccan adult male.
Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Askin's tumor is a rare, highly aggressive thoracopulmonary malignancy within the Ewing sarcoma family of tumors, predominantly affecting children and young adults, and is associated with a poor prognosis. We present a case of a 40-year-old male who is a current smoker with a 7-month history of a painful left anterior chest wall mass. Contrast-enhanced CT showed a large chest-wall tumor with rib lysis and pleural involvement. Histopathology confirmed a primitive neuroectodermal tumor, with immunohistochemistry positive for CD99, S-100, and synaptophysin. The patient was treated with VAC-IE poly-chemotherapy but experienced rapid radiological progression with extensive metastatic disease despite full-dose treatment. In the absence of an effective treatment for an aggressive disease, early intervention and multidisciplinary management are essential for timely control, prolonging survival while preserving quality of life.
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