Evidence map›Paper›PMID 42726310›Full record

ArticleCancer causes & control : CCC2026

Temporal trajectories of age at breast cancer diagnosis by socioeconomic and geographic factors: a 1975-2021 SEER analysis.

Soo Youn Bae, Chai Won Kim, Jehyun Chin, Jin Ah Lee, Dooreh Kim, Young Joo Lee, Chang Ik Yoon, Woo-Chan Park

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Article in Cancer causes & control : CCC, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Soo Youn BaeDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, South Korea. baessu@gmail.com.ORCID https://orcid.org/0000-0003-0551-7618
Chai Won KimGraduate School, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-9465-1151
Jehyun ChinDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, South Korea.ORCID http://orcid.org/0000-0002-0756-2319
Jin Ah LeeDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, South Korea.ORCID http://orcid.org/0009-0009-9107-8578
Dooreh KimDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, South Korea.ORCID http://orcid.org/0000-0003-1758-4439
Young Joo LeeDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, South Korea.ORCID http://orcid.org/0000-0001-5352-8093
Chang Ik YoonDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, South Korea.ORCID http://orcid.org/0000-0002-7273-8886
Woo-Chan ParkDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 06591, South Korea.ORCID http://orcid.org/0000-0002-1265-1981

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile overall breast cancer incidence and survival trends are well-documented, long-term shifts in age at diagnosis across diverse sociodemographic groups remain poorly understood. This study quantified stage-specific temporal changes in diagnostic age across racial, socioeconomic, and geographic subgroups over four decades to identify widening "diagnostic age gaps" and inform equitable screening policies.

methodsThis retrospective cohort study analyzed SEER 8 data (1975-2021) from 696,960 women with Stage I-III breast cancer. Annual mean age at diagnosis and rates of change (β1) were estimated using weighted ordinary least squares regression, stratified by stage, race, census tract-level income quartiles (Q1-Q4), and rural-urban continuum codes.

resultsThe overall mean age at diagnosis increased from 60.7 to 62.7 years. Black women showed the steepest annual increases in diagnostic age across all stages, yet remained younger at diagnosis than White women throughout the study period. However, a stark divergence was observed by income: high-income groups (Q4) showed significant increases, while low-income groups (Q1) and rural populations exhibited stagnant or declining diagnostic ages (e.g., Q1 Stage II β1= - 0.028).

conclusionsThe upward shift in breast cancer diagnostic age is largely absent among low-income and rural populations but present in higher-income, metropolitan groups. Black women showed the steepest increases yet remained the youngest at diagnosis. Equitable, subgroup-specific screening strategies are needed.

Indexed as

Breast NeoplasmsAdultAgedAge FactorsFemaleHumansLow Socioeconomic StatusMiddle AgedRetrospective StudiesRural PopulationSEER ProgramSocioeconomic Disparities in HealthSocioeconomic FactorsUnited StatesAge at diagnosisBreast cancerEpidemiologic trendsHealthcare disparitiesSocial determinants of healthSocioeconomic factors

Identifiers

PMID42726310

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.