ReviewCurrent cardiology reports2026
Beyond Angiography: Redefining The Gold Standard for Coronary Atherosclerosis.
Review in Current cardiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo examine the evolving paradigm of coronary artery disease [CAD] diagnosis beyond conventional coronary angiography and discuss how contemporary imaging modalities, coronary physiology, and artificial intelligence contribute to a more comprehensive assessment of coronary atherosclerosis. We explore whether the traditional stenosis-centered approach remains sufficient for risk stratification and clinical decision-making. RECENT
findingsRecent evidence has demonstrated that coronary risk is determined not only by luminal stenosis but also by plaque burden, plaque phenotype, vascular remodeling, inflammation, endothelial dysfunction, thrombogenicity, coronary physiology, microvascular integrity, and patient-level vulnerability. Intravascular ultrasound and optical coherence tomography provide detailed characterization of plaque morphology and vessel wall pathology, whereas fractional flow reserve and non-hyperemic pressure ratios identify flow-limiting epicardial disease. Coronary computed tomography angiography, combined with CT-derived fractional flow reserve, enables noninvasive evaluation of coronary anatomy, plaque characteristics, perivascular inflammation, and functional significance. Artificial intelligence is emerging as a powerful tool for integrating multimodality imaging and clinical data into individualized risk assessment and therapeutic planning. Coronary angiography remains fundamental for defining coronary anatomy and guiding revascularization but is no longer sufficient as a standalone reference standard for CAD evaluation. Contemporary diagnosis should integrate anatomical, biological, physiological, inflammatory, and patient-specific information to improve risk stratification and personalize treatment. Future advances will likely depend on multimodality imaging supported by artificial intelligence, enabling a precision cardiovascular medicine approach centered on the vulnerable patient rather than stenosis severity alone.
Indexed as
Identifiers
42726385What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.