Evidence map›Paper›PMID 42728215›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2026

Between-visit reproducibility of cerebrovascular and cardiovascular reactivity during the cold pressor test.

Joseph D Vondrasek, Jonathan W Hoch, Mu Huang, Luke N Belval, Caitlin P Jarrard, Craig G Crandall, Joseph C Watso

Abstract readComparative Study
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joseph D VondrasekCardiovascular and Applied Physiology Laboratory, Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0009-0006-8573-5955
Jonathan W HochCardiovascular and Applied Physiology Laboratory, Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0002-4992-1199
Mu HuangDepartment of Applied Clinical Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States.
Luke N BelvalInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-0929-8061
Caitlin P JarrardDepartment of Applied Clinical Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States.ORCID 0000-0002-6457-6805
Craig G CrandallInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-7792-9713
Joseph C WatsoCardiovascular and Applied Physiology Laboratory, Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0001-7840-0643

Funding

Time-Efficient Inspiratory Muscle Strength Training as a New Approach to Lower Blood Pressure, Improve Respiratory Function, and Reduce Exertional Dyspnea in Adults with ObesityK01HL160772 · NHLBI · FLORIDA STATE UNIVERSITY · PI Joseph Watso · 2022 to 2026
$693k
Inadequate Cardiovascular and Thermoregulatory Responses in the Elderly during Heat WavesF32HL154565 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI BELVAL, LUKE · 2020 to 2020
$60k
Ketamine-induced Hypertensive Episodes: Adverse Central and Peripheral Neurovascular ActionsF32HL154559 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI WATSO, JOSEPH · 2021 to 2021
$50k
American Heart Association (AHA) 23CDA1037938American Physiological Society (APS) Post-doc fellowshipHHS | National Institutes of Health (NIH) F32HL154559HHS | National Institutes of Health (NIH) F32HL154565HHS | National Institutes of Health (NIH) K01HL160772NHLBI NIH HHS F32 HL154559NHLBI NIH HHS F32 HL154565NHLBI NIH HHS K01 HL160772United States Army W81XWH-18-2-0012
6 · The paper itself

Abstract

The cold pressor test (CPT) is a painful test used to assess cardiovascular and cerebrovascular reactivity. Past studies examined between-visit reproducibility of cardiovascular reactivity during the CPT but not cerebrovascular reactivity. Therefore, we performed a retrospective analysis to test the hypothesis that cerebrovascular responses during the CPT would not differ and would have moderate relative agreement between visits. Fifty young adults free from overt disease, not taking pain-modifying medications, completed two trials ≥48 h apart. We measured middle cerebral artery blood velocity (MCAv) via transcranial Doppler ultrasound, beat-to-beat blood pressure (BP) via photoplethysmography, and end-tidal CO

Indexed as

Blood PressureCerebrovascular CirculationCold TemperatureMiddle Cerebral ArteryAdultBlood Flow VelocityFemaleHumansMalePhotoplethysmographyPredictive Value of TestsReproducibility of ResultsRetrospective StudiesTime FactorsUltrasonography, Doppler, TranscranialYoung Adultcerebrovascularcold pressor testpainreproducibility

Identifiers

PMID42728215
PMCPMC13637706

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.