Evidence map›Paper›PMID 42730185›Full record

ArticleCardiology research2026

Prolonged Mechanical Ventilation and In-Hospital Mortality Following Open-Heart Surgery: A Retrospective Cohort Study.

Jofinda Virsty, Muhammad Budi Kurniawan, Radian Ahmad Halimi, Dian Nuryanda, Reza Widianto Sudjud, Indriasari, Jenifer Kiem Aviani

Abstract read
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Article in Cardiology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jofinda VirstyFaculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia.
Muhammad Budi KurniawanCardiothoracic and Vascular Division, Intensive Care Division, Department of Anesthesiology and Intensive Care, Dr. Hasan Sadikin General Hospital, Padjadjaran University, Bandung, West Java, Indonesia.
Radian Ahmad HalimiSubdivision of Neuroanesthesia and Critical Care, Department of Anesthesiology and Intensive Therapy, Dr. Hasan Sadikin General Hospital, Padjadjaran University, Bandung, West Java, Indonesia.
Dian NuryandaDepartment of Anesthesiology and Intensive Therapy, Dr. Hasan Sadikin General Hospital, Padjadjaran University, Bandung, West Java, Indonesia.
Reza Widianto SudjudCardiothoracic and Vascular Division, Intensive Care Division, Department of Anesthesiology and Intensive Care, Dr. Hasan Sadikin General Hospital, Padjadjaran University, Bandung, West Java, Indonesia.
IndriasariSubdivision of Neuroanesthesia and Critical Care, Department of Anesthesiology and Intensive Therapy, Dr. Hasan Sadikin General Hospital, Padjadjaran University, Bandung, West Java, Indonesia.
Jenifer Kiem AvianiSubdivision of Neuroanesthesia and Critical Care, Department of Anesthesiology and Intensive Therapy, Dr. Hasan Sadikin General Hospital, Padjadjaran University, Bandung, West Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prolonged mechanical ventilation (PMV) after open-heart surgery is associated with adverse postoperative outcomes, but evidence regarding its association with mortality in Indonesia remains limited. This study evaluated the association between PMV and in-hospital mortality and identified factors associated with PMV. Methods: A retrospective cohort study was conducted among adults undergoing open-heart surgery at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, between 2023 and 2024. PMV was defined using two thresholds (> 24 h and ≥ 96 h). Factors associated with mortality were evaluated using univariable and multivariable logistic regression. Results: A total of 249 patients were included, with an in-hospital mortality rate of 18.9%. PMV occurred in 62.2% (> 24 h) and 5.6% (≥ 96 h) of patients. In multivariable analysis, PMV > 24 h (adjusted odds ratio (aOR) 3.259, 95% confidence interval (CI) 1.438-7.386; P = 0.005) and longer operative duration (aOR 1.009, 95% CI 1.004-1.015; P = 0.001) were associated with in-hospital mortality after adjustment. Using the ≥ 96-h definition, PMV (aOR 15.422, 95% CI 4.112-57.844; P < 0.001), operative duration (aOR 1.009, 95% CI 1.003-1.014; P = 0.002), and age (aOR 1.037, 95% CI 1.000-1.075; P = 0.049) remained associated with in-hospital mortality after adjustment. No statistically significant factors associated with PMV were identified. Conclusions: PMV was associated with increased in-hospital mortality following open-heart surgery, with a stronger association for ventilation ≥ 96 h. Longer operative duration also predicted mortality, highlighting the importance of perioperative risk stratification and optimized postoperative ventilatory management.

Indexed as

Binary logistic regressionIn-hospital mortalityOpen-heart surgeryProlonged mechanical ventilationReceiver operating characteristicsRisk factors

Identifiers

PMID42730185
PMCPMC13568775

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.