Optimizing Electrical Stimulation Parameters to Enhance Viability of Dental Pulp Stem Cells in Graphene-Based Scaffolds.

Mohammad Alsenaide, Dusan Losic, Said Al-Sarawi, Ryan O'Hare Doig

Abstract read

In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammad AlsenaideBiomedical Technology Department, College of Medical Applied Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID https://orcid.org/0000-0003-1586-4453

Dusan LosicSchool of Chemical Engineering, Adelaide University, Adelaide, South Australia 5005, Australia.ORCID https://orcid.org/0000-0002-1930-072X

Said Al-SarawiSchool of Electrical and Mechanical Engineering, Adelaide University, Adelaide, South Australia 5005, Australia.

Ryan O'Hare DoigNeil Sachse Centre for Spinal Cord Research, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia 5000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering (TE) combines cells, biomaterials, and external regulatory cues to support tissue repair and regeneration. Graphene-based scaffolds are promising TE platforms because they combine electrical conductivity, mechanical reinforcement, and cytocompatible surface properties. When paired with electrical stimulation (ES), these scaffolds may provide an electroactive microenvironment that influences stem cell behavior. However, suitable ES conditions for dental pulp stem cells (DPSCs) cultured on graphene-based scaffolds remain insufficiently defined. This study examined how different electric field (EF) intensities affect DPSC viability and cytotoxicity on graphene oxide/sodium alginate (GOSA) and reduced graphene oxide/sodium alginate (rGOSA) scaffolds. Three-dimensional scaffolds were prepared by freeze-drying, coated with poly-l-lysine (PLL), seeded with DPSCs, and stimulated using a custom Ti mesh electrode bioreactor. EF intensities from 0 to 500 mV mm

Identifiers

PMID42730202

DOI10.1021/acsomega.6c03534

PMCPMC13563962

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.