Evidence map›Paper›PMID 42731291›Full record

ArticleRedox biology2026

Injury polarized CD4

Thomas Wc Knight, Fatma Saaoud, Ngefor Asangwe, Ying Shao, Iman Khan, Hajime Kubo, Mohsin Khan, Hong Wang, Raj Kishore, Xiaofeng Yang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Thomas Wc KnightAging+Cardiac Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Fatma SaaoudLemole Center for Integrated Lymphatics and Vascular Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Ngefor AsangweAging+Cardiac Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Ying ShaoLemole Center for Integrated Lymphatics and Vascular Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Iman KhanAging+Cardiac Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Hajime KuboAging+Cardiac Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Mohsin KhanAging+Cardiac Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA; Department of Cellular and Molecular Medicine, Sarver Heart Center, University of Arizona, College of Medicine, Tucson, AZ, USA.
Hong WangCenter for Metabolic Disease Research and Thrombosis Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Raj KishoreAging+Cardiac Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.
Xiaofeng YangLemole Center for Integrated Lymphatics and Vascular Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA. Electronic address: xfyang@temple.edu.
Sadia MohsinAging+Cardiac Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA; Department of Cellular and Molecular Medicine, Sarver Heart Center, University of Arizona, College of Medicine, Tucson, AZ, USA. Electronic address: sadia.mohsin@temple.edu.

Funding

Small and large animal surgery, physiology and histologyP01HL134608 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI Douglas Tilley · 2017 to 2026
$21.0M
LysoPI/GPR55 pathway promotes endothelial activation, vascular inflammation and atherosclerosisR01HL163570 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI Xiaofeng Yang · 2023 to 2026
$2.6M
NHLBI NIH HHS P01 HL134608NHLBI NIH HHS R01 HL163570
6 · The paper itself

Abstract

Myocardial infarction (MI) initiates a wound-healing response where immune cells shape inflammation, tissue repair, and long-term remodeling. Although CD4

Indexed as

Cardiac repairCD4(+/TIP) T cellsInnate-like immunityMyocardial infarctionRedox signalingUnfolded protein response

Identifiers

PMID42731291
PMCPMC13587813

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.