ArticleiScience2026
Modifiable lifestyle factors and cancer risk in Latin America: A systematic review with meta-analysis.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer risk in Latin America is shaped by lifestyle exposures whose regional patterns are usually represented through extrapolated global estimates. We systematically reviewed observational studies on tobacco smoking, alcohol consumption, adiposity, physical inactivity, and dietary patterns and cancer risk in Latin American adults, searching four databases through September 2025 and appraising risk of bias with QUIPS. Forty-seven studies were included, almost all case-control. Pooling was restricted to site-specific sets sharing one exposure contrast, and only two qualified: a higher dietary inflammatory index with prostate cancer (OR 1.38, 95% CI 1.11-1.73) and obesity with endometrial cancer (OR 3.81, 1.08-13.45). In a direction-of-effect synthesis, healthy dietary exposures were protective in 9 of 9 estimates, whereas smoking and unhealthy diets were predominantly associated with increased risk. These associations are directional rather than causal, and they indicate where prospective regional cohorts are most needed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.