Evidence map›Paper›PMID 42734476›Full record

ArticleAmerican journal of physiology. Renal physiology2026

Differential regulation of basal and interferon-induced

Chunfa Huang, Zhenzhen Wu, Korey R Bartolomeo, John F O'Toole, John R Sedor, Leslie A Bruggeman

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chunfa HuangDepartment of Heart, Blood and Kidney Research, Cleveland Clinic Research, Cleveland, Ohio, United States.
Zhenzhen WuDepartment of Heart, Blood and Kidney Research, Cleveland Clinic Research, Cleveland, Ohio, United States.
Korey R BartolomeoDepartment of Kidney Medicine, Cleveland Clinic, Cleveland, Ohio, United States.ORCID 0000-0003-0738-111X
John F O'TooleDepartment of Heart, Blood and Kidney Research, Cleveland Clinic Research, Cleveland, Ohio, United States.
John R SedorDepartment of Heart, Blood and Kidney Research, Cleveland Clinic Research, Cleveland, Ohio, United States.ORCID 0000-0002-6780-9168
Leslie A BruggemanDepartment of Heart, Blood and Kidney Research, Cleveland Clinic Research, Cleveland, Ohio, United States.ORCID 0000-0001-5874-705X

Funding

Intracellular functions of APOL1 in the kidneyR01DK127638 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI BRUGGEMAN, LESLIE A, O'TOOLE, JOHN F. · 2021 to 2025
$2.8M
Mechanisms of Kidney Diseases Associated With APOL1 VariationR01DK135265 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI Leslie A Bruggeman, JOHN F. O'TOOLE · 2023 to 2026
$2.7M
KUH-TN Training CoreTL1DK132770 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI Evi X. Stavrou · 2021 to 2026
$2.5M
KUH-TN Professional Development CoreU2CDK129440 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI MIRELA AURORA DOBRE · 2021 to 2026
$2.0M
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01 DK127638HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01 Dk135265HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) TL1 DK132770HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) U2C DK129440NIDDK NIH HHS R01 DK127638NIDDK NIH HHS R01 DK135265NIDDK NIH HHS TL1 DK132770NIDDK NIH HHS U2C DK129440
6 · The paper itself

Abstract

Apolipoprotein L1 (

Indexed as

Apolipoprotein L1Interferon-gammaPodocytesApolipoproteinsCell LineGene Expression RegulationHumansInterferon Regulatory Factor-1Interferon-Stimulated Gene Factor 3, gamma SubunitPromoter Regions, GeneticSignal TransductionSTAT1 Transcription FactorAPOL1 protein, humanApolipoprotein L1ApolipoproteinsInterferon-gammaInterferon Regulatory Factor-1Interferon-Stimulated Gene Factor 3, gamma SubunitIRF1 protein, humanIRF9 protein, humanSTAT1 protein, humanSTAT1 Transcription FactorAPOL1gene regulationinterferon

Identifiers

PMID42734476
PMCPMC13628003

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.