Evidence map›Paper›PMID 42736787›Full record

Observational studyMedicine2026

Association between fear states and cognitive impairment: A cross-sectional observational study based on the China Health and Retirement Longitudinal Study (CHARLS).

Xiaoyun Hui, Kaikai Jiang, Jing Ji, Chunxuan Dong, Xiumei Xu

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoyun HuiDepartment of Rehabilitation Medicine, Wuwei People's Hospital, Wuwei, Gansu, 733099, China.
Kaikai JiangTianshui Maternal and Child Health Hospital, Tianshui, Gansu, 741000, China.
Jing JiDepartment of Rehabilitation Medicine, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou, Gansu, 730050, China.
Chunxuan DongDepartment of Rehabilitation Medicine, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou, Gansu, 730050, China.ORCID 0009-0006-8989-374
Xiumei XuDepartment of Rehabilitation Medicine, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou, Gansu, 730050, China.

Funding

based on HIF-1a regulation of iron death of hippocampal neurons, to explore the effect and mechanism of brain-buxing ointment in improving vascular dementia GZKZ-2024-1the 2022 construction project of inheritance studio of Sun Qibin, national famous old Chinese medicine expert Chinese Medicine Education Letter [2022] No. 75
6 · The paper itself

Abstract

As global populations age, the prevalence of cognitive impairment continues to rise, increasing the burden on families and society. This study examined the relationship between anxiety and cognitive function. Using nationally representative data from China Health and Retirement Longitudinal Study (CHARLS), this observational cohort study evaluated the association between fear states and cognitive impairment to provide objective scientific evidence on the potential causes of cognitive decline and to inform early prevention and treatment strategies. In this study, the prevalence of cognitive impairment was significantly higher among participants in the fearful group. After adjustment for multiple covariates, fearful state remained independently associated with cognitive impairment (odds ratio = 2.38, 95% confidence interval = 1.24-4.59, P = 9.52 × 10-3). Smooth curve fitting additionally confirmed this positive association. These findings demonstrate a significant association between fear state and cognitive impairment, highlighting the need to consider emotional well-being in cognitive health assessments.

Indexed as

AnxietyCognitive DysfunctionFearAgedChinaCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedPrevalenceRetirementAnxietyChina Health and Retirement Longitudinal StudyCognitive dysfunctionFearObservational study

Identifiers

PMID42736787
PMCPMC13574484

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.