Evidence map›Paper›PMID 42737673›Full record

ArticleInternational journal of molecular sciences2026

Chitosan Oligosaccharides Modulate Macrophage Inflammatory Signaling: Molecular Docking and Transcriptomic Evidence.

Yujun Sung, Siriporn Namwongsa, Sineenart Songkoomkrong, Supawadee Duangprom, Napamanee Kornthong

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yujun SungResearch Unit in Innovative Marine Biotechnology and Natural Bio-Resources for Sustainable Health and Wellness, Thammasat University, Pathum Thani 12120, Thailand.
Siriporn NamwongsaResearch Unit in Innovative Marine Biotechnology and Natural Bio-Resources for Sustainable Health and Wellness, Thammasat University, Pathum Thani 12120, Thailand.ORCID 0009-0007-4785-6251
Sineenart SongkoomkrongResearch Unit in Innovative Marine Biotechnology and Natural Bio-Resources for Sustainable Health and Wellness, Thammasat University, Pathum Thani 12120, Thailand.
Supawadee DuangpromResearch Unit in Innovative Marine Biotechnology and Natural Bio-Resources for Sustainable Health and Wellness, Thammasat University, Pathum Thani 12120, Thailand.ORCID 0000-0002-6307-8986
Napamanee KornthongResearch Unit in Innovative Marine Biotechnology and Natural Bio-Resources for Sustainable Health and Wellness, Thammasat University, Pathum Thani 12120, Thailand.

Funding

Research Fund of the Chulabhorn International College of Medicine, Thammasat University Grant No. T1/2565Thammasat University Research Unit in Innovative Marine Biotechnology and Natural Bio-resources for Sustainable Health and Wellness
6 · The paper itself

Abstract

Oxidative stress-induced macrophage activation and vascular injury are major contributors to atherosclerosis, a chronic inflammatory disease associated with approximately 20 million deaths worldwide. This study investigated the antioxidant and anti-inflammatory activities of structurally characterized low-molecular-weight chitosan oligosaccharides (COS) derived from mud crab (

Indexed as

Anti-Inflammatory AgentsChitosanInflammationMacrophagesOligosaccharidesSignal TransductionTranscriptomeAnimalsAntioxidantsCyclooxygenase 2MiceMolecular Docking SimulationNitric OxideNitric Oxide Synthase Type IIOxidative StressRAW 264.7 CellsAnti-Inflammatory AgentsAntioxidantsChitosanCyclooxygenase 2Nitric OxideNitric Oxide Synthase Type IIOligosaccharideschitosan oligosaccharidesinflammationmolecular dockingoxidative stresstranscriptomics

Identifiers

PMID42737673
PMCPMC13566840

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.