Severe Suprasystemic Refractory Pulmonary Hypertension in a Neonate with Stüve-Wiedemann Syndrome Associated with Biallelic LIFR Variants: Molecular Insights and a Neonatal Case Report.

Karolina Chojnacka, Greta Sibrecht, Karolina Gruca-Stryjak, Tomasz Szczapa

Abstract readCase Reports

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karolina ChojnackaNeonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit, II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.

Greta SibrechtNeonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit, II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-8905-7921

Karolina Gruca-StryjakDepartment of Perinatology, Gynecology and Obstetrics, Poznan University of Medical Sciences Clinical Hospital, 60-535 Poznan, Poland.ORCID 0000-0002-2898-4190

Tomasz SzczapaNeonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit, II Department of Neonatology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-5214-2719

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stüve-Wiedemann syndrome (SWS) is an ultra-rare autosomal recessive skeletal dysplasia caused by loss-of-function variants in the leukemia inhibitory factor receptor (

Indexed as

Exostoses, Multiple HereditaryHypertension, PulmonaryLeukemia Inhibitory Factor Receptor alpha SubunitOsteochondrodysplasiasPersistent Fetal Circulation SyndromeAllelesHumansInfant, NewbornLeukemia Inhibitory Factor Receptor alpha SubunitLIFR protein, humanechocardiographyendothelial-to-mesenchymal transition (EndMT)LIFR geneneonatal intensive carepersistent pulmonary hypertension of the newbornpulmonary vascular remodelingStüve–Wiedemann syndrome

Identifiers

PMID42737721

DOI10.3390/ijms27177824

PMCPMC13566290

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.