ReviewInternational journal of molecular sciences2026
Research Progress on Angiogenesis and Involution Mechanisms of Infantile Hemangioma and Its Regulation by Active Components of
Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
11 authors.
Funding
Abstract
Infantile hemangioma (IH) is the most common benign vascular tumor of infancy, characterized by a unique life cycle encompassing a rapid proliferative phase followed by spontaneous involution. Although the majority of cases exhibit a favorable prognosis, a small subset may be complicated by severe sequelae that adversely affect the physical and mental health of affected infants. Accumulating evidence indicates that the pathogenesis of IH involves a dynamic imbalance between angiogenesis and involution, which is tightly governed by the multilineage differentiation of hemangioma stem cells, core signaling pathway networks, and epigenetic regulation mediated by non-coding RNAs. A deeper understanding of the mechanisms underlying angiogenesis and involution will provide novel insights into both the fundamental biology and clinical management of IH. Furthermore, multiple bioactive constituents of the traditional Chinese medicine
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.