Evidence map›Paper›PMID 42737832›Full record

ArticleInternational journal of molecular sciences2026

Epithelial Inflammatory iNOS-Nitrate Axis Enhances

Linhesheng Wei, Hui Liu, Zongshan Shen, Zhi Song, Shuheng Huang, Zhengmei Lin, Xin Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linhesheng WeiGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0002-7445-4254
Hui LiuGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0003-2200-0063
Zongshan ShenGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Zhi SongGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Shuheng HuangGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Zhengmei LinGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0003-1586-3741
Xin HuangGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0001-9924-1055

Funding

China International Science and Technology Cooperation 2023A0505050158Guangzhou Experimental Station 2023A04J2154National Natural Science Foundation of China 82201056
6 · The paper itself

Abstract

The mechanisms by which host inflammatory responses reshape the pathogenic potential of oral microbiota in mucosal inflammatory diseases remain poorly defined. Metagenomic sequencing of subgingival plaque and single-cell RNA sequencing of gingival tissues were performed in patients with diabetes-associated periodontitis (DP) and non-diabetic periodontitis (P). A diabetic mouse model was used to evaluate inflammation and bone resorption following oral inoculation with

Indexed as

Diabetes Mellitus, ExperimentalNitratesNitric Oxide Synthase Type IIPeriodontitisPorphyromonas gingivalisVeillonellaAnimalsEpithelial CellsFemaleGingivaHumansInflammationMaleMiceVirulenceNitratesNitric Oxide Synthase Type IIdiabetes-associated periodontitishost–microbe interactioniNOSnitrateoral mucosal inflammationPorphyromonas gingivalisVeillonella parvula

Identifiers

PMID42737832
PMCPMC13566913

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.