ReviewCancers2026
PIK3CA in Cancer: Structure, Biology, Alterations, and Actionability.
Alessandro Ottaiano, Carmine Picone, Mariachiara Santorsola, Massimiliano Berretta, Carmen Cutolo, Andrea Belli, Francesco Izzo, Nadia Di Carluccio, Aniello Acampora, Luca Tarotto and 7 more
Abstract readReview
In one paragraphReview in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Alessandro OttaianoIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0000-0002-2901-3855 Carmine PiconeDepartment of Medicine and Health Science, "Vincenzo Tiberio" University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-5344-0056 Mariachiara SantorsolaIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Massimiliano BerrettaDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-9837-9148 Carmen CutoloIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Andrea BelliIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0000-0002-6252-573X Francesco IzzoIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0000-0003-3093-5408 Nadia Di CarluccioDepartment of Economics, University of Foggia, 71121 Foggia, Italy.
Aniello AcamporaIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Luca TarottoIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Salvatore StiloIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0009-0006-3295-840X Marco CorreraIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Maurizio CapuozzoPharmaceutical Department, Asl Napoli 3 Sud, Via Marittima 3, 80056 Ercolano, Italy.ORCID 0000-0002-3195-1883 Anna Chiara CarratùIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Michele CaragliaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.ORCID 0000-0003-2408-6091 Guglielmo NastiIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
PI3K signalingPIK3CAprecision oncologytargeted therapy
Identifiers
PMID42738319
PMCPMC13565655
What Socratic holds
Textmetadata
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