ArticleMolecules (Basel, Switzerland)2026
Cholesterol Quantification in Brain and Spinal Cord During Development, Demyelination, and Remyelination.
Disni Dedunupitiya, Eden P Go, Travis Witte, Ashlynn Elliott, Nishama De Silva Mohotti, Jenna M Williams, Hiroko Kobayashi, Rashmi Binjawadagi, Heather Desaire, Meredith D Hartley
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Disni DedunupitiyaDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.ORCID 0009-0007-6312-7163 Eden P GoDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Travis WitteDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Ashlynn ElliottDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Nishama De Silva MohottiDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Jenna M WilliamsDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Hiroko KobayashiDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Rashmi BinjawadagiDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
Heather DesaireDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.ORCID 0000-0002-2181-0112 Meredith D HartleyDepartment of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.ORCID 0000-0001-6229-2895 Funding
Understanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HOLMSTROM, ERIK D · 2012 to 2021
$22.1MWomen's Alzheimer's Risk Reduction in MidlifeP20GM152280 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HEATHER R DESAIRE · 2024 to 2026
$10.0MSynthetic Chemical Biology CoreP30GM145499 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI Susan M Lunte · 2022 to 2026
$6.9MNational Multiple Sclerosis Society RFA-2312-42463NIGMS NIH HHS P20 GM103638NIGMS NIH HHS P20GM103638NIGMS NIH HHS P20 GM152280NIGMS NIH HHS P20GM152280NIGMS NIH HHS P30 GM145499NIGMS NIH HHS P30GM145499Research Experiences for Undergraduates 1950293
6 · The paper itselfAbstract
Cholesterol in the central nervous system (CNS) is largely unesterified (>99%) and is predominantly present in the myelin sheath (~70% of total CNS cholesterol). However, cholesterol ester accumulation has been observed during neurological disease. In this cross-sectional study, we measured free cholesterol and cholesterol ester levels in the brains and the spinal cords of
Indexed as
BrainCholesterolDemyelinating DiseasesRemyelinationSpinal CordAnimalsCholesterol EstersDisease Models, AnimalGas Chromatography-Mass SpectrometryMiceMyelin SheathCholesterolCholesterol Esterscholesterolcholesterol estersdemyelinationgas chromatography mass spectrometry (GC-MS)liquid chromatography–mass spectrometry (LC-MS)multiple sclerosismyelinmyelin repairremyelination
Identifiers
PMID42738693
PMCPMC13566938
What Socratic holds
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