Evidence map›Paper›PMID 42738775›Full record

ArticleMolecules (Basel, Switzerland)2026

Prediction of Ocular Toxicity of Prostaglandin F

Xinyi Lu, Liping Ren, Chen Wang, Haiming Liao, Lisha Liu, Miaomiao Han, Lanying He, Dousheng Zhang, Huihong Fan, Mingzhe Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinyi LuSchool of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
Liping RenNational Institutes for Drug Control, Beijing 102629, China.
Chen WangNational Institutes for Drug Control, Beijing 102629, China.
Haiming LiaoNational Institutes for Drug Control, Beijing 102629, China.
Lisha LiuNational Institutes for Drug Control, Beijing 102629, China.
Miaomiao HanNational Institutes for Drug Control, Beijing 102629, China.
Lanying HeNational Institutes for Drug Control, Beijing 102629, China.
Dousheng ZhangNational Institutes for Drug Control, Beijing 102629, China.ORCID 0009-0005-2533-786X
Huihong FanNational Institutes for Drug Control, Beijing 102629, China.
Mingzhe XuNational Institutes for Drug Control, Beijing 102629, China.

Funding

State Key Laboratory of Drug Regulatory Science Project 2025SKLDRS0311
6 · The paper itself

Abstract

Drug-induced ocular toxicity is difficult to predict and evaluate, particularly for prostaglandin F2α (PGF2α) analogs used in the management of glaucoma. Traditional global predictive models, which are built with large and various datasets (

Indexed as

DinoprostAnimalsComputer SimulationGlaucomaHumansLatanoprostMachine LearningModels, MolecularRabbitsDinoprostLatanoprostcomputational modelslatanoprostocular toxicityPGF2αpredictionSIRT3virtual molecular docking

Identifiers

PMID42738775
PMCPMC13566995

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.