Evidence map›Paper›PMID 42740335›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Incidence and risk factors for AD/ADRD among American Indian and Alaska Native US Veterans.

Christina S Dintica, Amber Bahorik, Feng Xia, John Boscardin, Karen Parko, Kristine Yaffe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christina S DinticaDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0001-8186-8140
Amber BahorikDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.
Feng XiaNorthern California Institute for Research and Education, San Francisco, California, USA.
John BoscardinDepartment of Medicine, University of California, San Francisco, San Francisco, California, USA.
Karen ParkoDepartment of Neurology, University of California, San Francisco, San Francisco, California, USA.
Kristine YaffeDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.

Funding

Population Based Research for Alzheimer's Innovation (POP BRAIN)R35AG071916 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YAFFE, KRISTINE · 2021 to 2024
$3.8M
Department of Defense W81XWH-22-1-0961NIA NIH HHS R35 AG071916U.S. Department of Defense W81XWH-22-1-0961
6 · The paper itself

Abstract

introductionOur goal was to determine Alzheimer's disease (AD) and related dementias (ADRD) incidence and risk factors among American Indian and Alaska Native (AI/AN) veterans, an understudied group.

methodsWe identified AI/AN veterans ≥ 55 years receiving Veterans Health Administration care between 2005 and 2010 (n = 31,341) and a propensity score-matched non-Hispanic White (NHW) group for AD/ADRD (using International Classification of Diseases 9th/10th Revision codes from 2011-2023) incidence rate comparison. Age-adjusted incidence was calculated by direct standardization. Among AI/AN veterans, we determined dementia risk factors using Cox models.

resultsAmong 31,341 AI/AN veterans (mean age 67.8 years), 16.2% developed AD/ADRD over 9.3 years. Age-adjusted incidence was higher among AI/AN than NHW veterans (19.0 vs. 16.2 per 1000 person-years; incidence rate ratio: 1.17). Vascular conditions, traumatic brain injury, post-traumatic stress disorder, and depression were associated with risk of dementia among AI/AN veterans. DISCUSSION: AI/AN veterans experience higher AD/ADRD burden driven by modifiable risk factors, though findings may not generalize to non-veteran AI/AN populations.

Indexed as

Alzheimer DiseaseAmerican Indian or Alaska NativeDementiaVeteransAgedAged, 80 and overFemaleHumansIncidenceMaleMiddle AgedRisk FactorsUnited StatesAmerican Indian/Alaska Nativeincidenceriskveteran

Identifiers

PMID42740335
PMCPMC13575332

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.