Evidence map›Paper›PMID 42740873›Full record

ArticleJournal of geriatric cardiology : JGC2026

Lesion length-dependent effects of quantitative flow ratio-guided percutaneous coronary intervention.

De'an Jia, Qian-Yun Guo, Zhi-Jian Wang, Dong-Mei Shi, Jian'an Wang, Yun-Dai Chen, Jun Pu, Liang-Long Chen, Xin-Kai Qu, Jun-Qing Yang and 9 more

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In one paragraph

Article in Journal of geriatric cardiology : JGC, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

De'an Jia *Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Qian-Yun Guo *Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhi-Jian WangBeijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Dong-Mei ShiBeijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jian'an WangDepartment of Cardiology, National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yun-Dai ChenSecond Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jun PuThe Sixth Medical Centre, Chinese PLA General Hospital, Beijing, China.
Liang-Long ChenRenji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Xin-Kai QuFujian Medical University Union Hospital, Fuzhou, China.
Jun-Qing YangHuadong Hospital Affiliated to Fudan University, Shanghai, China.
Xue-Bo LiuGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Li-Jun GuoTongji Hospital, Tongji University School of Medicine, Shanghai, China.
Chang-Dong GuanPeking University Third Hospital, Beijing, China.
Yang WangPeking University Third Hospital, Beijing, China.
Yun-Fei HuangPeking University Third Hospital, Beijing, China.
Shu-Bin QiaoPeking University Third Hospital, Beijing, China.
Yu-Jie ZhouBeijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Beijing Institute of Heart Lung and Blood Vessel Disease, Clinical Center for Coronary Heart Disease, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Lei SongPeking University Third Hospital, Beijing, China.
Gregg W StoneWiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Cardiovascular Research Foundation, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The FAVOR III China trial previously revealed that quantitative flow ratio (QFR)-guided percutaneous coronary intervention (PCI) achieved superior outcomes compared with angiography guidance. This predefined subgroup analysis was conducted to examine whether coronary lesion length modifying the clinical effect of QFR based revascularization strategy. Methods: Overall, 3,825 patients were randomly assigned to either QFR-guided PCI (PCI performed only when QFR ≤ 0.80) or angiography-guided PCI. Lesions were categorized as long (≥ 20 mm) or short (< 20 mm), based on measurements from an independent imaging core laboratory. The primary study endpoint consisted of the composite of major adverse cardiac events (MACE), including myocardial infarction, ischemia-associated revascularization, and all-cause mortality over three years of follow-up. Results: A total of 1,877 patients were classified into the long-lesion group (931 QFR-guided and 946 angiography-guided), and 1,925 into the short-lesion group (974 QFR-guided, 951 angiography-guided). After three years, patients with longer lesions had a greater incidence of MACE relative to those with shorter lesions (15.5% Conclusions: QFR-guided PCI was linked to fewer MACE relative to PCI guided by angiography after three years. The relative benefit was most pronounced in patients with shorter lesions.

Identifiers

PMID42740873
PMCPMC13572094

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.