Evidence map›Paper›PMID 42740948›Full record

ReviewGastro hep advances2026

Assessment of Bowel Urgency in Ulcerative Colitis: Current Measures and Future Directions.

Marla Dubinsky, Richard Moses, Laurent Peyrin-Biroulet, Simon Travis, David T Rubin, Alissa Walsh, Alison Potts Bleakman, Charles Owen, Michael Camilleri

Abstract readReview
In one paragraph

Review in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marla DubinskySusan and Leonard Inflammatory Bowel Disease Clinical Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Richard MosesEli Lilly and Company, Indianapolis, Indiana.
Laurent Peyrin-BirouletDepartment of Gastroenterology, University Hospital of Nancy, University of Lorraine, Nancy, France.
Simon TravisTranslational Gastroenterology Unit, Experimental Medicine Division, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.
David T RubinInflammatory Bowel Disease Center, University of Chicago Medicine Inflammatory Bowel Disease Center, Chicago, Illinois.
Alissa WalshTranslational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Nuffield Department of Medicine Experimental Medicine Division, University of Oxford, Oxford, UK.
Alison Potts BleakmanEli Lilly and Company, Indianapolis, Indiana.
Charles OwenEli Lilly and Company, Indianapolis, Indiana.
Michael CamilleriClinical Enteric Neuroscience Translational and Epidemiological Research, Mayo Clinic, Rochester, Minnesota.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bowel urgency (BU), a burdensome ulcerative colitis (UC) symptom, impacts quality of life. It is associated with higher levels of disease severity, corticosteroid use, hospitalization, and colectomy. Despite its prevalence and clinical significance, BU is underassessed in clinical practice and infrequently included as a clinical trial end point. This review evaluates the strengths and limitations of available patient-reported outcome (PRO) measures assessing BU in UC to inform future directions for its assessment. A literature review was conducted using PubMed, Google Scholar, and Embase to identify publications through October 31, 2024, using the key terms "ulcerative colitis assessment" and "bowel urgency." Publications assessing BU in UC using PRO scales developed according to Food and Drug Administration guidance were included. Five tools met the inclusion criteria. The Urgency Numeric Rating Scale provides a simple and time-efficient tool for clinical use, while multi-item tools such as the Symptoms and Impacts Questionnaire for Ulcerative Colitis and the Ulcerative Colitis-Symptom Questionnaire include comprehensive symptom tracking but impose greater burdens for clinical practice. Diary-based tools, including the Ulcerative Colitis-Patient-Reported Outcomes/Signs and Symptoms Diary and Patient-Reported Outcomes-Ulcerative Colitis Diary, allow detailed symptom monitoring in clinical trials but are less practical for routine clinical use. Some dimensions of BU are missing from the tools reviewed. Incorporating validated BU measurement into routine clinical care and research is essential for advancing patient-centered, comprehensive disease management and improving outcomes in patients with UC.

Indexed as

AdultsFecal IncontinenceInflammatory Bowel DiseasesPatient-Reported OutcomesUlcerative Colitis

Identifiers

PMID42740948
PMCPMC13572057

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.