Evidence map›Paper›PMID 42741167›Full record

ArticleFrontiers in immunology2026

Cytokine signatures associated with persistent antibody responses to multiple

Sâmick L Moreira-Nascimento, Maria Fernanda A Nascimento, Gabriela M Fernandes, Sofia L Afonso, Victor H G Gunderman, Bárbara A Rodrigues, Stefanie C P Lopes, Camila Fabbri, Marcus V G Lacerda, Gregório G Almeida and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sâmick L Moreira-NascimentoFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Maria Fernanda A NascimentoFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Gabriela M FernandesFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Sofia L AfonsoFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Victor H G GundermanFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Bárbara A RodriguesFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Stefanie C P LopesFundação Oswaldo Cruz, Fiocruz, Instituto Leônidas e Maria Deane, Fiocruz Amazônia, Manaus, Amazonas, Brazil.
Camila FabbriFundação Oswaldo Cruz, Fiocruz, Instituto Leônidas e Maria Deane, Fiocruz Amazônia, Manaus, Amazonas, Brazil.
Marcus V G LacerdaFundação Oswaldo Cruz, Fiocruz, Instituto Leônidas e Maria Deane, Fiocruz Amazônia, Manaus, Amazonas, Brazil.
Gregório G AlmeidaFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Rhea J LongleyThe Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Ivo MuellerThe Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Lis R D V AntonelliFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Francis B NtumngiaCenter for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, FL, United States.
John H AdamsCenter for Global Health and Infectious Diseases Research, College of Public Health, University of South Florida, Tampa, FL, United States.
Andréa Teixeira-CarvalhoFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Luzia H CarvalhoFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Flora S KanoFundação Oswaldo Cruz, Fiocruz, Instituto René Rachou, Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.

Funding

Immunological characterization of the P. vivax DBPR01AI064478 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2006 to 2023
$9.6M
NIAID NIH HHS R01 AI064478
6 · The paper itself

Abstract

Introduction: Long-term humoral immunity to Methods: As a proof-of-concept, this study was designed to compare two well-defined immunological phenotypes among Results: Regardless of the antigen used for stimulation, Conclusion: Overall, these findings suggest that the PR profile is associated with a distinct and balanced cytokine profile. Our hypothesis-generating findings may improve our understanding of immune responses to

Indexed as

Antibodies, ProtozoanAntibody FormationAntigens, ProtozoanCytokinesMalaria, VivaxPlasmodium vivaxProtozoan ProteinsAdultFemaleFollow-Up StudiesHumansImmunity, HumoralImmunoglobulin GMalaria VaccinesMaleReceptors, Cell SurfaceAntibodies, ProtozoanAntigens, ProtozoanCytokinesDuffy antigen binding protein, PlasmodiumImmunoglobulin GMalaria VaccinesProtozoan ProteinsReceptors, Cell Surfaceblood-stage antigenscytokinesDuffy binding protein IIlong-term humoral immunitymalaria vaccinePlasmodium vivax

Identifiers

PMID42741167
PMCPMC13572285

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.