Evidence map›Paper›PMID 42741303›Full record

ArticleACS medicinal chemistry letters2026

Adenosine 5'-Carboxamide-Based Inhibitors of METTL1.

Olga Bobileva, Francesco Nai, Sandija Niedrite, Lidia Mayordomo Soler, Irena Leite, Amedeo Caflisch

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olga BobilevaLatvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV1006, Latvia.ORCID https://orcid.org/0000-0001-9600-1603
Francesco NaiDepartment of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.ORCID https://orcid.org/0000-0002-4258-3174
Sandija NiedriteLatvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV1006, Latvia.
Lidia Mayordomo SolerDepartment of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Irena LeiteLatvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV1006, Latvia.
Amedeo CaflischDepartment of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.ORCID https://orcid.org/0000-0002-2317-6792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

METTL1 is the human RNA methyltransferase that catalyzes the methylation of

Indexed as

dockingdrug discoveryepitranscriptomicsmethyltransferaseN7-guanosine

Identifiers

PMID42741303
PMCPMC13573248

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.