Evidence map›Paper›PMID 42742708›Full record

ArticleInternational urogynecology journal2026

Management of Mesh-Related Complications Following Uterovaginal Prolapse Repair: A Systematic Review.

Dylan T Wolff, Danielle Antosh, Maria J D'Amico, Fernanda Santis-Moya, Alexander Koven, Iryna Schmeil, Javier Pizarro-Berdichevsky, Jan Deprest, Amy Sisson, Howard B Goldman and 2 more

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Article in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dylan T WolffDepartment of Urology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Danielle AntoshDivision of Urogynecology, Department of Obstetrics and Gynecology, Houston Methodist Hospital, Houston, TX, USA.
Maria J D'AmicoGlickman Urologic Institute, Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA.
Fernanda Santis-MoyaCentro de Innovación en Piso Pélvico, Hospital Sotero del Rio, Santiago, Chile.
Alexander KovenGlickman Urologic Institute, Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA.
Iryna SchmeilDepartment of Gynecology and Obstetrics, Sana Klinikum Offenbach, Offenbach, Germany.
Javier Pizarro-BerdichevskyCentro de Innovación en Piso Pélvico, Hospital Sotero del Rio, Santiago, Chile.
Jan DeprestDepartment of Obstetrics and Gynaecology, University Hospitals KU Leuven, Leuven, Belgium.
Amy SissonCoy C. Carpenter Library, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Howard B GoldmanGlickman Urologic Institute, Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA.
Jacqueline ZilliouxDepartment of Urology, University of Virginia, Charlottesville, VA, USA.
Reut RotemDepartment of Urogynecology, Cork University Maternity Hospital, Cork, Ireland. Reutah86@gmail.com.ORCID http://orcid.org/0000-0002-4063-5911

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisMesh-based repairs for uterovaginal prolapse are associated with rare and potentially severe complications for which evidence-based management guidance remains limited. Our goal was to perform a systematic review of the literature and develop pragmatic management principles for mesh-related complications following uterovaginal prolapse repair.

methodsFollowing Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched MEDLINE and EMBASE through 11/11/25 for studies describing management of severe mesh-related complications following surgical repair of uterovaginal prolapse. Data collected included management strategies and clinical outcomes. Expert opinion and a modified Delphi process were used to develop consensus-based management algorithms and best practice statements.

resultsOf the 8890 abstracts screened, 56 studies met the inclusion criteria. The majority were small retrospective case series with overall low quality evidence. Vaginal mesh exposure was the most commonly reported complication, and management ranged from conservative to mesh excision. Mesh exposure involving visceral organs or fistula formation was associated with substantial morbidity, often presenting years after surgery, and frequently required multidisciplinary surgical management with mesh excision and repair of involved organs. Post-sacrocolpopexy lumbosacral discitis most commonly presented with lower back pain and elevated inflammatory markers. Selected patients were successfully managed with prolonged antibiotics alone, while most cases ultimately underwent surgical mesh excision.

conclusionsManagement of mesh-related complications following uterovaginal prolapse repair varies according to the location, severity, and extent of disease. Although the available evidence is limited, this review provides pragmatic management principles and treatment algorithms to support clinical decision-making in uncommon but potentially morbid complications.

Indexed as

AbscessMesh complicationMesh exposureProlapse complicationSacral discitisUterovaginal Prolapse

Identifiers

PMID42742708

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.