ReviewChinese medicine2026
The potential effects, mechanisms and translational perspectives of natural products in the treatment of atopic dermatitis.
Review in Chinese medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
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Abstract
backgroundAtopic dermatitis (AD) is a common chronic inflammatory skin disorder with a continuously increasing global incidence. Current therapeutic options are often associated with adverse effects. In recent years, natural products have attracted considerable attention due to their anti-inflammatory and antioxidant properties, which can effectively alleviate the symptoms of AD.
objectiveThis study provides a comprehensive review of the research progress on the use of natural ingredients for the treatment of AD both domestically and internationally, with an emphasis on their efficacy and advantages in the context of AD pathogenesis. The aim is to offer a reference for the development of herbal ingredients as safer complementary or alternative therapeutic agents for AD.
methodsA comprehensive literature search was performed using key terms such as "atopic dermatitis", "natural products", "anti-inflammatory", "skin barrier dysfunction", "anti-pruritic", "antimicrobial", "antioxidant", "gut microbiota", and their combinations in databases including CNKI, PubMed, and Google Scholar. We systematically evaluated the pathogenesis and therapeutic mechanisms of AD, with a particular emphasis on in vivo studies.
resultsResearch has demonstrated that natural ingredients exhibit multifaceted advantages in the treatment of AD, including anti-inflammatory effects, skin barrier repair, anti-pruritic activity, modulation of the skin microbiota, alleviation of oxidative stress, and regulation of gut microbiota.
conclusionWe discuss and analyze various bioactive natural ingredients capable of modulating cytokines and signaling pathways, while also identifying their major translational limitations, such as standardization and safety issues. This review provides a mechanistic and evidence-based reference for developing natural products as safe, adjunctive therapies for AD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.