Evidence map›Paper›PMID 42746261›Full record

ReviewFrontiers in immunology2026

Immunopathological mechanisms in autoimmune encephalitis: from pathogenesis to targeted therapies.

Ying-Ying Lu, Shan-Chao Zhang, Hai-Yun Li, Qi-Qing Yin, Yu-Qing Fang, Peng Zhou, Shan Qiao, Tao Xin

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ying-Ying Lu *Shandong First Medical University, Jinan, China.
Shan-Chao Zhang *Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Hai-Yun LiQilu Hospital of Shandong University, Jinan, China.
Qi-Qing YinShandong First Medical University, Jinan, China.
Yu-Qing FangDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Peng ZhouDepartment of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Shan QiaoDepartment of Neurology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Tao XinDepartment of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune encephalitis (AE) is an antibody-mediated brain disorder involving self-antibody-driven inflammation. Different subtypes present unique clinical and pathological features, influenced by variations in target antigens and underlying pathophysiological processes. Although the precise pathogenesis of each AE subtype remains incompletely understood, recent research has provided valuable insights into their immunopathological mechanisms. This article critically evaluates current discoveries regarding the immunobiology of diverse autoimmune encephalitis categories, elucidating their multifaceted etiological pathways. Furthermore, this review highlights the potential of targeted therapeutic interventions, and personalized treatment strategies, thereby facilitating the translation of mechanism discoveries into precision medicine.

Indexed as

EncephalitisHashimoto DiseaseAnimalsAutoantibodiesHumansMolecular Targeted TherapyPrecision MedicineAutoantibodiesautoimmune encephalitisimmune regulationimmunological diversitymolecular mechanismsprecision medicine

Identifiers

PMID42746261
PMCPMC13575755

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.