Evidence map›Paper›PMID 42746291›Full record

ArticlePatterns (New York, N.Y.)2026

OpenChallenges: A FAIR-aligned, centralized platform for crowdsourced challenges in biomedical research.

Verena Chung, Rongrong Chai, Hallie Swan, Maria Diaz, Shysta Bynum, Adam Hindman, Jacob Albrecht, Serghei Mangul, Susheel Varma, Jay Hodgson and 5 more

Abstract read
In one paragraph

Article in Patterns (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Verena ChungSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Rongrong ChaiSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Hallie SwanSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Maria DiazSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Shysta BynumSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Adam HindmanSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Jacob AlbrechtSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Serghei MangulSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Susheel VarmaSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Jay HodgsonSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Solveig K SiebertsSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Alberto PepeSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Luca FoschiniSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Thomas SchaffterSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.
Gaia AndreolettiSage Bionetworks, 2901 3rd Ave. #330, Seattle, WA 98121, USA.

Funding

Advancing method benchmarking and data sharing through crowd-sourced competitions in cancer researchU24CA248265 · NCI · SAGE BIONETWORKS · PI BOUTROS, PAUL CHRISTOPHER, VARMA, SUSHEEL · 2020 to 2024
$4.1M
NCI NIH HHS U24 CA248265
6 · The paper itself

Abstract

Open community challenges are critical for benchmarking computational methods in biomedical research, but the landscape is highly fragmented. Currently, over 2,000 challenges exist across a large and fragmented set of platforms, yet no centralized registry exists to index them. To address this, we developed OpenChallenges, a centralized, FAIR (Findable, Accessible, Interoperable, and Reusable)-aligned hub that aggregates and standardizes challenge metadata from diverse sources into a single, searchable registry. By implementing an updated metadata model explicitly mapped to FAIR dimensions, the platform advances challenge discoverability. A metadata completeness scoring framework assigns each challenge one of four tiers (baseline, standard, comprehensive, and gold standard), providing users with a transparent measure of metadata richness and guiding community curation priorities. Built on an open-source, API-driven architecture, OpenChallenges streamlines discovery, enhances visibility, and supports community-driven curation. This resource transforms a fragmented ecosystem into an interconnected knowledge base, advancing transparency in computational biology.

Indexed as

biomedical benchmarkingcommunity challengescomputational biologycrowdsourcingdata standardizationFAIR principlesopen sciencereproducibility

Identifiers

PMID42746291
PMCPMC13576655

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.