ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026
Psychiatric consultation outcomes in deep brain stimulation candidacy: clinical and psychosocial correlates from a retrospective cohort.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesPreoperative psychiatric assessment in deep brain stimulation (DBS) candidacy extends beyond contraindication screening to include informed consent capacity and psychosocial preparedness. This study examined factors associated with psychiatric consultation outcomes in DBS candidates.
methodsThis retrospective single-centre study reviewed 363 patients referred for preoperative psychiatric consultation at Etlik City Hospital between September 2022 and January 2026. Outcomes were classified as "suitable," "conditionally suitable," or "not suitable." Associations were assessed using univariate analyses, with multinomial logistic regression including NMS restricted to the Parkinson's disease subgroup.
resultsOutcomes were "suitable," "conditionally suitable," and "not suitable" in 66.9%, 22.6%, and 10.5% of patients, respectively. Among patients with Parkinson's disease, psychiatric history was present in 35.3% and NMS in 73.5%. In the adjusted subgroup model, limited/absent support, insufficient informed-consent capacity, and NMS were correlates of "conditionally suitable" status, whereas limited/absent support, insufficient consent capacity, impaired cognitive status, and psychiatric history were correlates of "not suitable" status (psychiatric history: aOR = 5.513, 95% CI 1.941-15.657, p = 0.001). As these variables contributed to outcome classification, they should be interpreted as correlates rather than independent predictors. Age, sex, education, and SMMSE score were not significantly associated with outcome.
conclusionsWithin the Parkinson's disease subgroup, social/care support, informed-consent capacity, psychiatric history, and NMS were associated with consultation outcome, whereas demographic factors and SMMSE score were not. Cognitive status showed only a category-specific association with the "not suitable" outcome and should be interpreted cautiously. These findings support structured psychiatric assessment in multidisciplinary DBS candidate selection.
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