Evidence map›Paper›PMID 42747783›Full record

ArticleApplied biochemistry and biotechnology2026

Synthesis of Padina boergesenii-Derived Zinc Oxide Nanoparticles and their Therapeutic Potential Against Oral Squamous Cell Carcinoma: A Transcriptomic and in Vitro Evaluation.

Ashok Kumar, Sheikh F Ahmad, Sabry M Attia, S Winkins Santosh, Uday Aditya Sarkar, R Magesh, Rashu Barua, Shiek Ssj Ahmed

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Article in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashok KumarDrug Discovery and Multi-omics Laboratory, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, 603103, Tamil Nadu, India.
Sheikh F AhmadDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Sabry M AttiaDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
S Winkins SantoshToxicology Research on Endocrine Disruptors Laboratory (TRENDS Lab), PG & Research, Department of Advanced Zoology & Biotechnology, Government Arts College, Nandanam, Chennai, 6000035, Tamil Nadu, India.
Uday Aditya SarkarDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
R MageshDepartment of Biotechnology, Sri Ramachandra Institute of Higher Education and Research, Chennai, 600116, Tamil Nadu, India.
Rashu BaruaFoundations of Medicine, Diabetes and Obesity Center, New York University Grossman Long Isalnd School of Medicine, Mineola, NY, 11501, USA.
Shiek Ssj AhmedDrug Discovery and Multi-omics Laboratory, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, 603103, Tamil Nadu, India. shiekssjahmed@gmail.com.

Funding

King Saud University ORF-2026-748
6 · The paper itself

Abstract

Cancer remains a major health challenge, with oral squamous cell carcinoma (OSCC) being an high aggressive subtype of head and neck squamous cell carcinoma that lacks effective therapeutic options. Current study integrates the synthesis of zinc oxide nanoparticles (ZnO-NPs) from the marine brown algae Padina boergesenii with the OSCC gene expression profile to evaluate their potential therapeutic effects against OSCC. Herein, the ZnO-NPs from Padina boergesenii were prepared through the green synthesis method. The obtained ZnO-NPs were characterized through spectroscopic methods, the UV spectrophotometer shows maximum absorbance at 372 nm, FT-IR presents Zn-O functional band at 516 cm

Indexed as

CytotoxicityInteraction networkOral squamous cell carcinomaTherapeutic targetZnO-NPs

Identifiers

PMID42747783

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.