Evidence map›Paper›PMID 42749732›Full record

Articlenpj aging2026

Associations of physical fitness with brain structure, pathology and cognition in cognitively normal older adults.

Svenja Schwarck, Niklas Behrenbruch, Beate Schumann-Werner, Eóin N Molloy, Berta Garcia-Garcia, Anne Hochkeppler, Larissa Fischer, Anna-Therese Büchel, Enise I Incesoy, Jose Bernal and 16 more

Abstract read
In one paragraph

Article in npj aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Svenja SchwarckGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Niklas BehrenbruchGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.ORCID http://orcid.org/0009-0002-7947-9220
Beate Schumann-WernerGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Eóin N MolloyGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Berta Garcia-GarciaGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Anne HochkepplerGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Larissa FischerGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.ORCID http://orcid.org/0009-0001-9936-2954
Anna-Therese BüchelGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Enise I IncesoyGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Jose BernalGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Roberto Duarte CoelloDepartment of Neuroimaging Sciences, Row Fogo Centre for Research into Ageing and The Brain, Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-2952-2163
Maria D C Valdés-HernándezDepartment of Neuroimaging Sciences, Row Fogo Centre for Research into Ageing and The Brain, Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-2771-6546
Joanna M WardlawDepartment of Neuroimaging Sciences, Row Fogo Centre for Research into Ageing and The Brain, Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-9812-6642
Niklas VockertGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Patrick MüllerGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Gusalija BehnischLeibniz Institute for Neurobiology (LIN), Magdeburg, Germany.
Barbara MorgadoDepartment for Psychiatry and Psychotherapy, University Medical Center Göttingen (UMG), Göttingen, Germany.
Hermann EsselmannDepartment for Psychiatry and Psychotherapy, University Medical Center Göttingen (UMG), Göttingen, Germany.
Constanze I SeidenbecherLeibniz Institute for Neurobiology (LIN), Magdeburg, Germany.
Björn H SchottLeibniz Institute for Neurobiology (LIN), Magdeburg, Germany.
Henryk BarthelDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
Osama SabriDepartment of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
Jens WiltfangDepartment for Psychiatry and Psychotherapy, University Medical Center Göttingen (UMG), Göttingen, Germany.
Michael C KreisslGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Emrah DüzelGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Anne MaassGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany. anne.maass@dzne.de.

Funding

Deutsche Forschungsgemeinschaft 362321501Deutsche Forschungsgemeinschaft 425899996
6 · The paper itself

Abstract

The role of physical fitness in cognitive reserve and brain maintenance remains unclear. We investigated the associations of muscular and aerobic fitness (VO

Identifiers

PMID42749732
PMCPMC13582920

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.